BDBM50583067 CHEMBL5083331::US11739089, Compound 16
SMILES COc1cc(NC(=O)c2cc(=O)c3ccccc3o2)c(cc1OCc1ccccc1)-c1nnn(n1)-c1ccc(CCN2CCc3cnccc3C2)cc1
InChI Key InChIKey=RZBYWYQCFTUDRA-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50583067
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using IPA as substrate preincubated for 10 mins followed by NADPH generating system addition and measu...More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of wild type human P-gp in human MES-SA/Dx5 cells incubated for 3 days by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds, DMSO (negative control), and ketoconazole (positive control) were diluted to 4× final concentrations in water. The standard final Com...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Test compounds, DMSO (negative control), and ketoconazole (positive control) were diluted to 4× final concentrations in water. The standard final Com...More data for this Ligand-Target Pair