BDBM50583012 CHEMBL5075142

SMILES Cc1ccc(NC(=O)c2cc(OCCO)nc(c2)C(F)(F)F)cc1-c1ccc2NC(=O)CC3(CCOCC3)Oc2c1

InChI Key InChIKey=LFROYMIRGMXUFQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50583012   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Eternity Bioscience

Curated by ChEMBL
LigandPNGBDBM50583012(CHEMBL5075142)
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant cRAF measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed