BDBM50582978 CHEMBL5094293

SMILES Cc1ccc(NC(=O)c2ccnc(c2)C(F)(F)F)cc1-c1ccc2CNCC3(CCOCC3)Oc2c1

InChI Key InChIKey=GXEPTJRUPJBHAM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50582978   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Eternity Bioscience

Curated by ChEMBL
LigandPNGBDBM50582978(CHEMBL5094293)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human recombinant cRAF measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed