BDBM50582946 CHEMBL5092701

SMILES NS(=O)(=O)c1ccc(NC(=O)CCN2CCN(CC2)c2cc3n(cc(C(O)=O)c(=O)c3cc2F)C2CC2)cc1

InChI Key InChIKey=DLXOHRWBSQWBAJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50582946   

TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50582946(CHEMBL5092701)
Affinity DataIC50: 600nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 assessed as reduction in decatenation using kDNA as substrate incubated for 30 mins by fluorimetr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50582946(CHEMBL5092701)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoiling activity using pBR322 as substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed