BDBM50582940 CHEMBL5084320

SMILES [#7]\[#6](-[#7])=[#7]\S(=O)(=O)c1ccc(cc1)\[#7]=[#7]\[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]1)-c1cc2n(cc(-[#6](-[#8])=O)c(=O)c2cc1F)-[#6]-1-[#6]-[#6]-1

InChI Key InChIKey=WGOYSWNJUFXXEL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50582940   

TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50582940(CHEMBL5084320)
Affinity DataIC50: 640nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 assessed as reduction in decatenation using kDNA as substrate incubated for 30 mins by fluorimetr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50582940(CHEMBL5084320)
Affinity DataIC50: 770nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoiling activity using pBR322 as substrate incubated for 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed