BDBM50582875 CHEMBL5091203::US20240327387, Compound 11 (PO05)

SMILES COc1nc(NCCNC(C)=O)nc(OCc2cccc(c2C)-c2ccccc2)n1

InChI Key InChIKey=IMGYIJIRUBAPJO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50582875   

TargetProgrammed cell death 1 ligand/protein 1(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50582875(CHEMBL5091203 | US20240327387, Compound 11 (PO05))
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of human recombinant PD-1/PDL-1 interaction measured by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50582875(CHEMBL5091203 | US20240327387, Compound 11 (PO05))
Affinity DataIC50: 1.53E+3nMAssay Description:As further confirmation of the results of the NMR assay and to classify the compounds of the invention based on their in vitro ability to inhibit PD-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
Go to US Patent