BDBM50582870 CHEMBL5084981::US20240327387, Compound 7 (MAP55)

SMILES CC(=O)NCCCNc1ncnc(OCc2cccc(c2C)-c2ccccc2)n1

InChI Key InChIKey=BRTFIZOCYLZIHX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50582870   

TargetProgrammed cell death 1 ligand/protein 1(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50582870(CHEMBL5084981 | US20240327387, Compound 7 (MAP55))
Affinity DataIC50: 2.15E+3nMAssay Description:Inhibition of human recombinant PD-1/PDL-1 interaction measured by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50582870(CHEMBL5084981 | US20240327387, Compound 7 (MAP55))
Affinity DataIC50: 2.15E+3nMAssay Description:As further confirmation of the results of the NMR assay and to classify the compounds of the invention based on their in vitro ability to inhibit PD-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2025
Entry Details
Go to US Patent