BDBM50582675 CHEMBL5074667

SMILES CC(=O)OCC(=O)N1CCC2=Nc3c(ccc(Cl)c3Cl)C2(C1)Nc1ccccc1C=O

InChI Key InChIKey=TXISWAUNDMCHBW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50582675   

TargetCyclic GMP-AMP synthase(Human)
Shanghai Institute of Materia Medica (Simm)

Curated by ChEMBL
LigandPNGBDBM50582675(CHEMBL5074667)
Affinity DataIC50: 9.59E+3nMAssay Description:Inhibition of human cGAS expressed in THP1-Dual cells transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed