BDBM50582540 CHEMBL5085291

SMILES [O-][N+](=O)c1ccc(NC(=O)COc2ccc3cc(\C=C4\SC(=O)NC4=O)ccc3c2)cc1

InChI Key InChIKey=CZWQVHMBWIVBNF-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50582540   

TargetHistone deacetylase 4(Human)
Bharati Vidyapeeth'S College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50582540(CHEMBL5085291)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of recombinant human HDAC4 using Boc-Lys (trifluoroacetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Bharati Vidyapeeth'S College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50582540(CHEMBL5085291)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of recombinant human HDAC8 using Boc-Lys (trifluoroacetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Bharati Vidyapeeth'S College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50582540(CHEMBL5085291)
Affinity DataEC50:  1.61E+3nMAssay Description:Partial agonist activity at Gal4-fused human PPARgamma LBD in HepG2 cells assessed as transactivation incubated for 20 hrs measured by luminometerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed