BDBM50582443 CHEMBL5077087

SMILES CC(=O)N1Cc2nc(N3CCC(CC3)Oc3ccc(F)cc3F)c(NC3CC3)nc2C=C1

InChI Key InChIKey=UJPWZSCQYUJKMV-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50582443   

TargetG-protein coupled receptor 6(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50582443(CHEMBL5077087)
Affinity DataEC50:  3.40E+4nMAssay Description:Inverse agonist activity at human GPR6 expressed in CHO-K1 cells assessed as modulation of cAMP level incubated for 20 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50582443(CHEMBL5077087)
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed