BDBM50582439 CHEMBL5078045

SMILES CC(C)Nc1nc2CN(C=Cc2nc1N1CCN(Cc2ccc(F)cc2F)CC1)C(C)=O

InChI Key InChIKey=POURVRUOWXYLQO-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50582439   

TargetG-protein coupled receptor 6(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50582439(CHEMBL5078045)
Affinity DataEC50:  2.70E+4nMAssay Description:Inverse agonist activity at human GPR6 expressed in CHO-K1 cells assessed as modulation of cAMP level incubated for 20 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50582439(CHEMBL5078045)
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed