BDBM50582435 CHEMBL4762823

SMILES CC(C)Nc1nc2cc(C)ncc2nc1N1CCC(CC1)Oc1ccc(F)cc1F

InChI Key InChIKey=INCGEZFRJSPDKD-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50582435   

TargetG-protein coupled receptor 6(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50582435(CHEMBL4762823)
Affinity DataEC50:  1.60E+4nMAssay Description:Inverse agonist activity at human GPR6 expressed in CHO-K1 cells assessed as modulation of cAMP level incubated for 20 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50582435(CHEMBL4762823)
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed