BDBM50582396 CHEMBL5093186

SMILES CCN(C1CCOCC1)c1cc(cc(C(=O)NCc2c(C)cc(C)n(C)c2=O)c1C)-c1ccc(CN2CCN(CCCCCCCOc3cccc4C(=O)N(C5CCC(=O)NC5=O)C(=O)c34)CC2)cc1

InChI Key InChIKey=NSMNQZZPPLGEIM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50582396   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50582396(CHEMBL5093186)
Affinity DataIC50: 23nMAssay Description:Inhibition of N-terminal His-tagged EZH2 in human PRC2 complex (2 to end residues) expressed in Sf9 cells using [3H]-SAM as substrate preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed