BDBM50582382 CHEMBL5085848

SMILES CC[C@H](C)n1cc(C)c2c(cc(cc12)-c1ccc(nc1)N1CCN(CCCCCCCCCOc2cccc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c23)CC1)C(=O)NCc1c(C)cc(C)[nH]c1=O

InChI Key InChIKey=CPVGAEUHQZBYRI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50582382   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50582382(CHEMBL5085848)
Affinity DataIC50: 16nMAssay Description:Inhibition of N-terminal His-tagged EZH2 in human PRC2 complex (2 to end residues) expressed in Sf9 cells using [3H]-SAM as substrate preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed