BDBM50582357 CHEMBL5076046

SMILES ONC(=O)CCCCCCn1cc(Nc2ncc3ccn(-c4ccc(Cl)cc4)c3n2)cn1

InChI Key InChIKey=QSSQMXDNNSWKPH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50582357   

TargetHistone deacetylase 6(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50582357(CHEMBL5076046)
Affinity DataIC50: 33nMAssay Description:Inhibition of HDAC6 (unknown origin) incubated for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50582357(CHEMBL5076046)
Affinity DataIC50: 48nMAssay Description:Inhibition of JAK2 (unknown origin) preincubated for 60 mins followed by reagent A addition and measured after 60 mins in presence of ATP by using mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed