BDBM50582229 CHEMBL5080633

SMILES CC(F)(F)CNC(=O)C(CC(F)F)c1ccc2[nH]c(nc2c1F)[C@@H](NC(=O)c1nonc1C1CC1)C1CCC(F)(F)CC1

InChI Key InChIKey=AZPAJNMBZHHBAB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50582229   

TargetInterleukin-17A(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50582229(CHEMBL5080633)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of IL-17A in human HDF cells assessed as IL-6 release incubated for 5 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed