BDBM50582137 CHEMBL5078188

SMILES Cc1c(Br)cc(C(=O)NCC(=O)Nc2ccc3NC(=O)\C(=C/c4cnc[nH]4)c3c2)c(=O)n1Cc1ccc(F)c(F)c1

InChI Key InChIKey=PFXPIFJDEXHSIO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50582137   

LigandPNGBDBM50582137(CHEMBL5078188)
Affinity DataIC50: 134nMAssay Description:Inhibition of recombinant full length human His-tagged PDK1 expressed in Baculovirus expression system in presence of ATP measured by Bradford protei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetAurora kinase A(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50582137(CHEMBL5078188)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant full length human His-tagged AURA expressed in Baculovirus expression system in presence of ATP measured by Bradford protei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed