BDBM50581725 CHEMBL5081862

SMILES CC12CC3CC(CC(C1)c1ccccc31)(C2)NC(=O)N[C@H]1CC[C@@H](CC1)Oc1ccc(cc1)C(O)=O

InChI Key

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50581725   

TargetBifunctional epoxide hydrolase 2(Human)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50581725(CHEMBL5081862)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50581725(CHEMBL5081862)
Affinity DataIC50: 9.90nMAssay Description:Inhibition of mouse recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50581725(CHEMBL5081862)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of rat recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50581725(CHEMBL5081862)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant LOX-5 preincubated for 10 mins in presence of AA and ATP measured after 20 mins by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCytochrome c oxidase subunit 2(Human)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50581725(CHEMBL5081862)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50581725(CHEMBL5081862)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human recombinant CYP2C19 preincubated for 5 mins in presence of NADP+ by fluorescent assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed