BDBM50581720 CHEMBL5080024::US20240182406, Example C4

SMILES CC12CC3CC(CC(C1)c1ccccc31)(C2)NC(=O)Nc1ccc(F)c(F)c1F

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50581720   

TargetBifunctional epoxide hydrolase 2(Human)
Unitat Associada Al Csic

Curated by ChEMBL
LigandPNGBDBM50581720(CHEMBL5080024 | US20240182406, Example C4)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetEpoxide hydrolase 1(Human)
Universitat De Barcelona

US Patent
LigandPNGBDBM50581720(CHEMBL5080024 | US20240182406, Example C4)
Affinity DataIC50: 1.10nMAssay Description:The fluorescent assay was used with purified recombinant human or mouse sEH proteins. The enzymes were incubated at 30° C. with the inhibitors ([I]fi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
Go to US Patent