BDBM50581479 CHEMBL5069682

SMILES COc1ccc(cc1OC)N(C1CCN(C)CC1)C(=S)NCCCn1cncc1C

InChI Key InChIKey=RGPGHWMCXHFPCU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50581479   

TargetGlutaminyl-peptide cyclotransferase(Human)
Beijing University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581479BDBM50581479(CHEMBL5069682)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of recombinant human glutaminyl cyclase (QC) using H-Gln-AMC as substrate incubated for 20 mins prior to rhPGPEP1 addition and measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Beijing University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581479BDBM50581479(CHEMBL5069682)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed