BDBM50581435 CHEMBL5089539

SMILES COc1cc(ccc1OCCc1ccnc(N)c1)N(C1CCN(C)CC1)C(=O)NCCCn1cncc1C

InChI Key InChIKey=LUXVBQYXNBNAIG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50581435   

TargetGlutaminyl-peptide cyclotransferase(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50581435(CHEMBL5089539)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase-like protein(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50581435(CHEMBL5089539)
Affinity DataIC50: 19nMAssay Description:Inhibition of isoQC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Mouse)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50581435(CHEMBL5089539)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of mouse QPCT measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed