BDBM50581391 CHEMBL1962723

SMILES NC(=O)[C@H](CCCNC(=N)CF)NC(=O)c1ccccc1

InChI Key InChIKey=OLFDULIIJWCYCK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50581391   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Zhejiang Ocean University

Curated by ChEMBL
LigandPNGBDBM50581391(CHEMBL1962723)
Affinity DataIC50: 2.16E+4nMAssay Description:Inhibition of PDE4 (unknown origin) in presence of calcium by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Zhejiang Ocean University

Curated by ChEMBL
LigandPNGBDBM50581391(CHEMBL1962723)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of PDE4 (unknown origin) in absence of calcium by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProtein-arginine deiminase type-4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50581391(CHEMBL1962723)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of N-terminal full length recombinant human PAD4 expressed in Escherichia coli Rosetta cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed