BDBM50581279 CHEMBL5087098

SMILES CS(=O)(=O)Nc1ccc(CNC(=O)c2ccc(CC(F)(F)F)cc2)c(Cl)c1

InChI Key InChIKey=VMALQYUTALFADG-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50581279   

TargetBile acid receptor(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50581279(CHEMBL5087098)
Affinity DataEC50:  4.00E+3nMAssay Description:Agonist activity at recombinant human full-length FXR expressed in HeLa cells co-expressing human RXRalpha after 24 hrs by Dual-Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50581279(CHEMBL5087098)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human sEH using PHOME as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed