BDBM50581275 CHEMBL5082993

SMILES CS(=O)(=O)Nc1ccc(CNC(=O)c2ccc(cc2)C23CC(C2)C3)c(Cl)c1

InChI Key InChIKey=OAWLHXXTRZGHPR-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50581275   

TargetBile acid receptor(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50581275(CHEMBL5082993)
Affinity DataEC50:  560nMAssay Description:Agonist activity at recombinant human full-length FXR expressed in HeLa cells co-expressing human RXRalpha after 24 hrs by Dual-Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50581275(CHEMBL5082993)
Affinity DataIC50: 49nMAssay Description:Inhibition of recombinant human sEH using PHOME as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed