BDBM50581266 CHEMBL5080537

SMILES CC(C)S(=O)(=O)Nc1ccc(CNC(=O)c2ccc(cc2)C(C)(C)C)c(Cl)c1

InChI Key InChIKey=DEDSYKQSMZFCKD-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50581266   

TargetBifunctional epoxide hydrolase 2(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50581266(CHEMBL5080537)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human sEH using PHOME as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50581266(CHEMBL5080537)
Affinity DataEC50:  420nMAssay Description:Agonist activity at recombinant human full-length FXR expressed in HeLa cells co-expressing human RXRalpha after 24 hrs by Dual-Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed