BDBM50581264 CHEMBL5079511

SMILES CC(C)(O)c1ccc(cc1)C(=O)NCc1ccc(NS(C)(=O)=O)cc1Cl

InChI Key InChIKey=MMIXUSJYTSMKEI-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50581264   

TargetBile acid receptor(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50581264(CHEMBL5079511)
Affinity DataEC50:  32nMAssay Description:Agonist activity at recombinant human full-length FXR expressed in HeLa cells co-expressing human RXRalpha after 24 hrs by Dual-Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50581264(CHEMBL5079511)
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant human sEH using PHOME as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed