BDBM50581237 CHEMBL5081888

SMILES Cc1nc(OCc2ccccc2)c2c(c[nH]c2n1)-c1ccnc(N)c1

InChI Key InChIKey=MLAPBLMPGXKRBF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50581237   

LigandPNGBDBM50581237(CHEMBL5081888)
Affinity DataIC50: 12nMAssay Description:Inhibition of DYRK1A (unknown origin) assessed as accumulation of ADP by ADP hunter plus assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandPNGBDBM50581237(CHEMBL5081888)
Affinity DataIC50: 17nMAssay Description:Inhibition of DYRK1A (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandPNGBDBM50581237(CHEMBL5081888)
Affinity DataIC50: 13nMAssay Description:Inhibition of DYRK1B (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50581237(CHEMBL5081888)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK9 (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50581237(CHEMBL5081888)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PIM1 (unknown origin) by ADP hunter plus assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandPNGBDBM50581237(CHEMBL5081888)
Affinity DataIC50: 400nMAssay Description:Inhibition of DYRK2 (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed