BDBM50581236 CHEMBL5090676

SMILES Cc1nc(OCc2cncs2)c2c(c[nH]c2n1)-c1ccnc(N)c1

InChI Key InChIKey=UBGUCDLLEIGHHP-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50581236   

LigandPNGBDBM50581236(CHEMBL5090676)
Affinity DataIC50: 12nMAssay Description:Inhibition of DYRK1A (unknown origin) assessed as accumulation of ADP by ADP hunter plus assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandPNGBDBM50581236(CHEMBL5090676)
Affinity DataIC50: 15nMAssay Description:Inhibition of DYRK1A (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandPNGBDBM50581236(CHEMBL5090676)
Affinity DataIC50: 1nMAssay Description:Inhibition of DYRK1B (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50581236(CHEMBL5090676)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK9 (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50581236(CHEMBL5090676)
Affinity DataIC50: 360nMAssay Description:Inhibition of PIM1 (unknown origin) by ADP hunter plus assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50581236(CHEMBL5090676)
Affinity DataIC50: 99nMAssay Description:Inhibition of TTK (unknown origin) by ADP hunter plus assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandPNGBDBM50581236(CHEMBL5090676)
Affinity DataIC50: 2nMAssay Description:Inhibition of DYRK2 (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50581236(CHEMBL5090676)
Affinity DataIC50: 24nMAssay Description:Inhibition of CLK (unknown origin) by TR FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed