BDBM50581179 CHEMBL5078680

SMILES [O-][n+]1cc(Cl)c(C[C@H](OC(=O)c2cccc(NC(C(=O)O[C@H]3CN4CCC3CC4)c3ccccc3)c2)c2ccc(OC(F)F)c(OCC3CC3)c2)c(Cl)c1

InChI Key InChIKey=FMMIDZWTNQYEIY-UHFFFAOYSA-N

Data  1 KI  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50581179   

TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
Chiesi Farmaceutici

Curated by ChEMBL

LigandBDBM50581179(CHEMBL5078680)Copy SMILESCopy InChI

Affinity DataIC50: 1nMAssay Description:Inhibition of PDE4 in human U-937 cells assessed as reduction in cAMP level by LANCE cAMP AssayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/5/2023
Entry Details Article
Copy Entry DOIPubMed
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TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

Curated by ChEMBL

LigandBDBM50581179(CHEMBL5078680)Copy SMILESCopy InChI

Affinity DataKi:  0.794nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/5/2023
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL