BDBM50581158 CHEMBL5084695

SMILES COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2P(C)(C)=O)n1)N1CCC(CC1)N1CCN(CC1)C(=O)CNc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12

InChI Key InChIKey=AQGLXXCBEXDRNS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50581158   

TargetALK tyrosine kinase receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50581158(CHEMBL5084695)
Affinity DataIC50: 2.5nMAssay Description:Binding affinity to ALK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50581158(CHEMBL5084695)
Affinity DataIC50: 6.60nMAssay Description:Binding affinity to ALK G1202R mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed