BDBM50581155 CHEMBL5083117

SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](OP(O)(O)=O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)C(=O)NCCC(=O)NCCSCCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O

InChI Key InChIKey=OGNKJQUKEAVEJP-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50581155   

TargetN-alpha-acetyltransferase 40(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50581155(CHEMBL5083117)
Affinity DataIC50: 40nMAssay Description:Inhibition of human NatD using H4-8 peptide substrate at Km value and AcCoA measured after 30 min incubation by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetN-alpha-acetyltransferase 40(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50581155(CHEMBL5083117)
Affinity DataIC50: 41nMAssay Description:Inhibition of human NatD using H4-8 peptide substrate at 4 times Km value and AcCoA measured after 30 min incubation by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetN-alpha-acetyltransferase 40(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50581155(CHEMBL5083117)
Affinity DataKi:  8.40nMAssay Description:Inhibition of human NatD using H4-8 peptide substrate at Km value and AcCoA by Morrison's quadratic equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed