BDBM50581120 CHEMBL5085978

SMILES Clc1ccc(CN2CCn3c(nc4cccc(Br)c34)C2=O)cc1

InChI Key InChIKey=MNMMYRNEABEESW-UHFFFAOYSA-N

Data  1 IC50  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50581120   

TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL

LigandBDBM50581120(CHEMBL5085978)Copy SMILESCopy InChI

Affinity DataEC50:  30nMAssay Description:Positive allosteric modulator activity at human mGlu2 receptor expressed in rat Chem-1 cells assessed as cytosolic Ca2+ ion concentration measured af...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/5/2023
Entry Details Article
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Gedeon Richter

Curated by ChEMBL

LigandBDBM50581120(CHEMBL5085978)Copy SMILESCopy InChI

Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human ERG by patch clamp electrophysiology assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/5/2023
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL