BDBM50581111 CHEMBL5081320

SMILES Fc1ccc(cc1)-c1cccc2nc3C(=O)N(CC4CC4)CCn3c12

InChI Key InChIKey=OHLNCNITYGSIRH-UHFFFAOYSA-N

Data  1 IC50  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50581111   

TargetMetabotropic glutamate receptor 2(Human)
Gedeon Richter

Curated by ChEMBL

LigandBDBM50581111(CHEMBL5081320)Copy SMILESCopy InChI

Affinity DataEC50:  580nMAssay Description:Positive allosteric modulator activity at human mGlu2 receptor expressed in rat Chem-1 cells assessed as cytosolic Ca2+ ion concentration measured af...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/5/2023
Entry Details Article
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Gedeon Richter

Curated by ChEMBL

LigandBDBM50581111(CHEMBL5081320)Copy SMILESCopy InChI

Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of human ERG by patch clamp electrophysiology assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/5/2023
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL