BDBM50580968 CHEMBL5083020

SMILES CNC(=O)Nc1cc2CC[C@@]3(OC(=O)N(CC(=O)N4Cc5ccc(F)cc5CC[C@H]4C4CC4)C3=O)c2cc1F

InChI Key InChIKey=GGXPWHYWZIJKLJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50580968   

TargetHistone acetyltransferase p300(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580968(CHEMBL5083020)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of p300 (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCREB-binding protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580968(CHEMBL5083020)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of CBP (unknown origin) preincubated for 15 mins followed by addition of substrate [3H] Ac-CoA and measured after 60 mins by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed