BDBM50580873 CHEMBL5081898

SMILES COc1ccc(NC(=O)c2cccnc2Nc2cccc(Cl)c2C)cc1

InChI Key InChIKey=LMRZMKVQRBRGBG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50580873   

TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50580873(CHEMBL5081898)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated 10 mins followed by substrate addition and measured after 2 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50580873(CHEMBL5081898)
Affinity DataIC50: 6.12E+4nMAssay Description:Inhibition of human topoisomerase I using DNA pBR322 as substrate assessed as DNA relaxation incubated for 45 mins by ethidium bromide staining based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed