BDBM50580869 CHEMBL5078291

SMILES COc1ccc(CCCNC(=O)c2ccccc2Nc2ccccc2)cc1

InChI Key InChIKey=XUNFCCMYMSNWQM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50580869   

TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50580869(CHEMBL5078291)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated 10 mins followed by substrate addition and measured after 2 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50580869(CHEMBL5078291)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of human topoisomerase I using DNA pBR322 as substrate assessed as DNA relaxation incubated for 45 mins by ethidium bromide staining based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed