BDBM50580629 CHEMBL5085564

SMILES COc1cc(cc(OC)c1OC)-c1cc(nn1-c1ccccc1)C(=O)CCCOc1ccc2ccc(=O)oc2c1

InChI Key InChIKey=YSDPUYIVKPNWKQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50580629   

TargetProstaglandin G/H synthase 1(Sheep)
TBA

Curated by ChEMBL
LigandPNGBDBM50580629(CHEMBL5085564)
Affinity DataIC50: 5.31E+4nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2 mins by EI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50580629(CHEMBL5085564)
Affinity DataIC50: 230nMAssay Description:Inhibition of human COX-2 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2 mins by EI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed