BDBM50580628 CHEMBL5089355

SMILES [#8]-[#6@H](-[#6]-[#8]-c1cc(-[#8])c2c(c1)oc(cc2=O)-c1ccccc1)-[#6]-n1cc(\[#6]=[#6]-2\[#6](=O)-[#7]-[#6](=O)-[#7]-[#6]-2=O)c2ccccc12

InChI Key InChIKey=CNVHMRPZVLPMPR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50580628   

TargetProstaglandin G/H synthase 1(Sheep)
TBA

Curated by ChEMBL
LigandPNGBDBM50580628(CHEMBL5089355)
Affinity DataIC50: 340nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2 mins by EI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50580628(CHEMBL5089355)
Affinity DataIC50: 1nMAssay Description:Inhibition of human COX-2 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2 mins by EI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed