BDBM50580625 CHEMBL5081272

SMILES COC(=O)[C@H](Cc1ccccc1)n1nncc1COc1ccc2ccccc2c1-c1c(OCc2cnnn2[C@@H](Cc2ccccc2)C(=O)OC)ccc2ccccc12

InChI Key InChIKey=MZIGZAUPIQLDMX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50580625   

TargetProstaglandin G/H synthase 1(Sheep)
TBA

Curated by ChEMBL
LigandPNGBDBM50580625(CHEMBL5081272)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2 mins by EI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50580625(CHEMBL5081272)
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of human COX-2 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2 mins by EI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed