BDBM50580508 CHEMBL5094949::US20240122876, Example 11

SMILES CCCC(CCC)COc1cc(ccc1F)[C@@H](O)CCN

InChI Key InChIKey=WDYVEMOTVIKKNU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50580508   

TargetRetinoid isomerohydrolase(Bovine)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580508(CHEMBL5094949 | US20240122876, Example 11)
Affinity DataIC50: 177nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetRetinoid isomerohydrolase/Retinaldehyde-binding protein 1(Human)
Case Western Reserve University

US Patent
LigandPNGBDBM50580508(CHEMBL5094949 | US20240122876, Example 11)
Affinity DataIC50: 177nMAssay Description:Primary amine listed in Table 2 in DMF (1 μL) was added into a suspension containing 300 μg of RPE microsomal proteins, 1% bovine serum alb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent