BDBM50580500 CHEMBL5077356::US20240122876, Example 20

SMILES CCCC(CCC)COc1cc(F)cc(c1)C(O)CCN

InChI Key InChIKey=BLOWDQMWLLKIPK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50580500   

TargetRetinoid isomerohydrolase(Bovine)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580500(CHEMBL5077356 | US20240122876, Example 20)
Affinity DataIC50: 184nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetRetinoid isomerohydrolase(Bovine)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580500(CHEMBL5077356 | US20240122876, Example 20)
Affinity DataIC50: 184nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetRetinoid isomerohydrolase/Retinaldehyde-binding protein 1(Human)
Case Western Reserve University

US Patent
LigandPNGBDBM50580500(CHEMBL5077356 | US20240122876, Example 20)
Affinity DataIC50: 184nMAssay Description:Primary amine listed in Table 2 in DMF (1 μL) was added into a suspension containing 300 μg of RPE microsomal proteins, 1% bovine serum alb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetRetinoid isomerohydrolase/Retinaldehyde-binding protein 1(Human)
Case Western Reserve University

US Patent
LigandPNGBDBM50580500(CHEMBL5077356 | US20240122876, Example 20)
Affinity DataIC50: 295nMAssay Description:Primary amine listed in Table 2 in DMF (1 μL) was added into a suspension containing 300 μg of RPE microsomal proteins, 1% bovine serum alb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent