BDBM50580356 CHEMBL5079764

SMILES Clc1cnc(COc2cc3c(cc(cc3cn2)C(=O)N2CCC(CC2)(C#N)c2ccccc2)C(=O)N2CCCCC2)c(Cl)c1

InChI Key InChIKey=XXCQOAIPHDTBIU-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50580356   

TargetCoagulation factor XI(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50580356(CHEMBL5079764)
Affinity DataEC50:  19nMAssay Description:Inhibition of human coagulation factor 11 assessed as inhibition of factor 12a mediated activation using z-GPR-AFC measured after 60 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed