BDBM50580355 CHEMBL5093463

SMILES O=C(N1CCC(CC1)(C#N)c1ccccc1)c1cc(C(=O)N2CCCCC2)c2cc(OCCCc3cccnc3)ncc2c1

InChI Key InChIKey=QVQWOEMOKOSJNV-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50580355   

TargetCoagulation factor XI(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50580355(CHEMBL5093463)
Affinity DataEC50:  8.5nMAssay Description:Inhibition of human coagulation factor 11 assessed as inhibition of factor 12a mediated activation using z-GPR-AFC measured after 60 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed