BDBM50580194 CHEMBL5074977

SMILES [H][C@@]12C[C@@H]([C@H](CC)CN1CC[C@@]1(O)C2=Nc2cccc(C)c12)C(=C/OC)\C(=O)OC

InChI Key InChIKey=SRWPJHWJHYRESN-UHFFFAOYSA-N

Data  1 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50580194   

TargetMu-type opioid receptor(Human)
University of Health Sciences & Pharmacy At St. Louis

Curated by ChEMBL
LigandPNGBDBM50580194(CHEMBL5074977)
Affinity DataEC50:  5.30nMAssay Description:Agonist activity at human MOR expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulation incubated for 30 mins by Gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Health Sciences & Pharmacy At St. Louis

Curated by ChEMBL
LigandPNGBDBM50580194(CHEMBL5074977)
Affinity DataEC50:  5.20nMAssay Description:Agonist activity at human MOR expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulation incubated for 30 mins by Gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Health Sciences & Pharmacy At St. Louis

Curated by ChEMBL
LigandPNGBDBM50580194(CHEMBL5074977)
Affinity DataEC50:  1.04E+4nMAssay Description:Agonist activity at human MOR receptor expressed in HTLA cells co-expressing TEV-fused-beta-arrestin2 assessed as induction of beta-arrestin2 recruit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Health Sciences & Pharmacy At St. Louis

Curated by ChEMBL
LigandPNGBDBM50580194(CHEMBL5074977)
Affinity DataEC50:  1.05E+4nMAssay Description:Agonist activity at human MOR receptor expressed in HTLA cells co-expressing TEV-fused-beta-arrestin2 assessed as induction of beta-arrestin2 recruit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Health Sciences & Pharmacy At St. Louis

Curated by ChEMBL
LigandPNGBDBM50580194(CHEMBL5074977)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]-DAMGO from mu opioid receptor (unknown origin) expressed in CHO cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed