BDBM50580056 CHEMBL5086750

SMILES CCCCCCCSSCC\C=C\[C@@H]1CC(=O)NCc2nc(cs2)C(=O)N\C(=C/C)C(=O)N[C@@H](CCCCN)C(=O)O1

InChI Key InChIKey=ZGKVKLQBOOZORR-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50580056   

TargetHistone deacetylase 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580056(CHEMBL5086750)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human full length HDAC11 expressed in baculovirus infected Sf9 cells measured after 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580056(CHEMBL5086750)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of recombinant human C-terminal FLAG/His-tagged HDAC1 (1 to 482 residues) expressed in Sf9 insect cells using fluorometric substrate measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580056(CHEMBL5086750)
Affinity DataIC50: 10nMAssay Description:Inhibition of C-terminal His-tagged recombinant human HDAC3 (1 to 428 residues)/N-terminal GST-tagged recombinant human NCoR2 (395 to 489 residues) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580056(CHEMBL5086750)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of recombinant human full length C-terminal His- tagged HDAC2 (1 to 488 residues) expressed in Sf9 insect cells using fluorometric substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580056(CHEMBL5086750)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cells using fluorometric substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580056(CHEMBL5086750)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged/C-terminal His-tagged HDAC4 (627 to 1084 residues) expressed in baculovirus infected Sf9 insect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580056(CHEMBL5086750)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged HDAC5 expressed in baculovirus infected Sf9 insect cells using fluorogenic substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580056(CHEMBL5086750)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HDAC7 expressed in baculovirus infected Sf9 insect cells using fluorogenic substrate measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580056(CHEMBL5086750)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human C-terminal His-tagged HDAC9 (604 to 1066 residues) expressed in baculovirus infected Sf9 insect cells using fluorogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580056(CHEMBL5086750)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged HDAC6 expressed in Sf9 cells using fluorogenic substrate measured after 60 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50580056(CHEMBL5086750)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human N-terminal FLAG tagged HDAC10 (2 to 631 residues) expressed in baculovirus infected Sf9 insect cells using fluorogeni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed