BDBM50579977 CHEMBL5086139

SMILES CCOc1ccc(nc1)-c1nnc([C@H]2C[C@@H](C2)NC(=O)c2cccc3nc(C)cnc23)n1-c1ccccc1F

InChI Key InChIKey=VFEHXRALKSTBML-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50579977   

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Symeres

Curated by ChEMBL
LigandPNGBDBM50579977(CHEMBL5086139)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed