BDBM50579952 CHEMBL5076581

SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](Cc2ccc(Cl)cc2)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O)C(=O)NCC(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H](CCCNC(N)=N)C(O)=O

InChI Key InChIKey=JBVPOLBOSKNBGA-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50579952   

TargetMu-type opioid receptor(Human)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50579952(CHEMBL5076581)
Affinity DataEC50:  14nMAssay Description:Agonist activity at mu-opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50579952(CHEMBL5076581)
Affinity DataKi:  5.80nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50579952(CHEMBL5076581)
Affinity DataKi:  2.09E+3nMAssay Description:Displacement of [3H]DPDPE from DOR in Wistar rat brain membranes measured after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50579952(CHEMBL5076581)
Affinity DataKi:  3.17E+3nMAssay Description:Displacement of [3H]-U69593 from KOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed