BDBM50579855 CHEMBL5082422

SMILES CC#CC(=O)Nc1cccc(c1)-c1nccc(n1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O

InChI Key InChIKey=XCLDOUBHTACKMM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50579855   

TargetEpidermal growth factor receptor(Human)
Acerta Pharma

Curated by ChEMBL
LigandPNGBDBM50579855(CHEMBL5082422)
Affinity DataIC50: 499nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin) preincubated for 60 mins followed by substrate addition and further incubated for 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed