BDBM50579526 CHEMBL4878564

SMILES Cc1ccc(cc1)C1=C(c2nnn[nH]2)C(=O)N[C@@](C1)(c1ccc(OCCCCCC(F)(F)F)cc1)C(F)(F)F

InChI Key InChIKey=WDLHNOKAVCEXRE-UHFFFAOYSA-N

Data  8 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50579526   

TargetAlpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Human)
TBA

Curated by ChEMBL

LigandBDBM50579526(CHEMBL4878564)Copy SMILESCopy InChI

Affinity DataIC50: 6.10nMAssay Description:Inhibition of human recombinant MGAT2 expressed in Sf9 cell membrane using 2-monooleglycerol and [H3]-oleoyl-CoA as substrates incubated for 20 mins ...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/25/2022
Entry Details Article
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TargetAlpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Mouse)
TBA

Curated by ChEMBL

LigandBDBM50579526(CHEMBL4878564)Copy SMILESCopy InChI

Affinity DataIC50: 12nMAssay Description:Inhibition of mouse recombinant MGAT2 expressed in Sf9 cell membrane using 2-oleoylglycerol and oleoyl-CoA as substrates incubated for 10 mins by LCM...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/25/2022
Entry Details Article
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TargetAlpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Rat)
TBA

Curated by ChEMBL

LigandBDBM50579526(CHEMBL4878564)Copy SMILESCopy InChI

Affinity DataIC50: 8.60nMAssay Description:Inhibition of rat recombinant MGAT2 expressed in Sf9 cell membrane using 2-oleoylglycerol and oleoyl-CoA as substrates incubated for 10 mins by LCMS ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/25/2022
Entry Details Article
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TargetBeta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase(Human)
TBA

Curated by ChEMBL

LigandBDBM50579526(CHEMBL4878564)Copy SMILESCopy InChI

Affinity DataIC50: 820nMAssay Description:Inhibition of human MGAT3More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/25/2022
Entry Details Article
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TargetAcyl-CoA wax alcohol acyltransferase 2(Human)
TBA

Curated by ChEMBL

LigandBDBM50579526(CHEMBL4878564)Copy SMILESCopy InChI

Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human AWAT2More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/25/2022
Entry Details Article
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TargetDiacylglycerol O-acyltransferase 1(Human)
TBA

Curated by ChEMBL

LigandBDBM50579526(CHEMBL4878564)Copy SMILESCopy InChI

Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human DGAT1More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/25/2022
Entry Details Article
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TargetStanniocalcin-1(Human)
TBA

Curated by ChEMBL

LigandBDBM50579526(CHEMBL4878564)Copy SMILESCopy InChI

Affinity DataIC50: 13nMAssay Description:Inhibition of human STC1 in cell based assayMore data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/25/2022
Entry Details Article
Copy Entry DOIPubMed
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TargetStanniocalcin-1(Mouse)
TBA

Curated by ChEMBL

LigandBDBM50579526(CHEMBL4878564)Copy SMILESCopy InChI

Affinity DataIC50: 20nMAssay Description:Inhibition of mouse STC1 in cell based assayMore data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/25/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL