BDBM50578956 CHEMBL4853162

SMILES CSc1ccc(cc1NC(=O)c1ccc(cc1)-c1ccccc1)C(=O)NO

InChI Key InChIKey=PZHHLVFWYKDPSX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50578956   

TargetHistone deacetylase 8(Blood fluke)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50578956(CHEMBL4853162)
Affinity DataIC50: 100nMAssay Description:Inhibition of Schistosoma mansoni HDAC8 using Fluor de Lys as substrate incubated for 90 mins by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50578956(CHEMBL4853162)
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant HDAC8 using H2N-Arg-His-Lys(Ac)-Lys(Ac)-AMC as substrate after 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50578956(CHEMBL4853162)
Affinity DataIC50: 3.88E+3nMAssay Description:Inhibition of recombinant human HDAC1 using ZMAL as substrate incubated for 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50578956(CHEMBL4853162)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant human HDAC6 using ZMAL as substrate incubated for 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed